So, there are scenarios that make Eagle Eyes the best mutation in the game, and many more scenarios that make it useless. Also not that great with disc guns.Įagle Eyes - 2 (5 if you get the right weapon) This is essential for any run that is using a bolt weapon. The ability to kill a room full of weak guys with 1 shot is insane. However, when you do have a bolt weapon, this kicks ass. Generally speaking, it is not worth the risk of taking this mutation without a weapon that benefits from it. Unfortunately, in the grand scheme of things,this doesn't really help much to make your run faster, just safer, so it only gets a 3.īolt Marrow - 3 (5 if you have a bolt weapon) Not only will this mutation allow you to hit things at close range, but it saves you from things like car explosions, those suicide bombers in the labs, and it allows you to essentially stand on top of the throne when it explodes, cutting a second or two from your time. While explosions are great for killing large groups of weak enemies and can still kill a single high hp target without much trouble, the fact that they cannot kill anything at close range without killing you is a huge downside. Personally, I despise using explosive weapons. It doesn't really make you win any faster, so it is essentially a waste of a slot. Picking this up early can usually lead to you having an ammo supply higher than your previous maximum capacity, but that will generally be depleted fairly quickly, making it dead weight for what could be a much faster run if another mutation was taken instead.īloodlust offers us a decent amount of survivability, but at the cost of an uncontrollable negative synergy with Stress. Having a huge stockpile of ammo is essential for lasting as long as possible, but that is not our goal here. So many people love this mutation when playing to loop. If you only have mutations that are 3 and lower, go for Patience and hope for the best.Ĥ. Essentially, if you have anything at 4 or higher, take that instead of Patience. I believe Patience is a very important mutation, and I'm sure most of you will find yourselves taking it very often. If you get this on your first level in a 1 Character run, I would probably reset unless I have some really good weapons.ģ.5. It is a definite benefit to your run, but there is still probably better. Only helps slightly, and should probably be ignored as well.ģ. The proper utilization of this mutation will most likely cost you time.Ģ. To get a better idea of this rating scaleġ. This will be in alphabetical order, and each mutation will be given a rating from 1-5. With that in mind, I want to analyze each mutation and determine how useful it would be in a speedrun. I am a believer that having good mutation RNG is one of the most important factors to having a fast run, maybe even more important than good weapon RNG. I figured it would be important to have a few tips for new players, so here we are. It just means that it isn't on the same level as the mutations in B tier.Ī: Trigger Fingers, Bloodlust, Melting Throne Butt, Rebel Throne Butt, Scarier Face, Boiling Veins, Rabbit Paw, Laser Brain, Bolt Marrowī: Plant Throne Butt, Impact Wrists, Steroids Throne Butt, Second Stomache, Long Arms, Robot Throne Butt, Hammer Head, Crystal Throne Butt, Eyes Throne Butt, Horror Throne Butt, Rogue Throne Butt, Back MuscleĬ: Rhino Skin, Y.V.Hello, and welcome to a guide on mutations. If a certain mutation is in C tier, it doesn't mean it is bad. Mutations that are in the same tier can be comfortably taken interchangeably with each other.ĭon't be put off by the tier letter that a certain mutation is in. Not taking into account mutants' individual passive traits.Īssuming the goal is to get as many kills as possible, in the loop.įeel free to comment your suggestions on how this tier list could be improved.
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